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NMNAT3
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'''Nicotinamide mononucleotide adenylyltransferase 3''' is an [[enzyme]] that in humans is encoded by the ''NMNAT3'' [[gene]].<ref name="pmid11027696">Liquid error: wrong number of arguments (given 1, expected 2)</ref>
NMNAT3 is the third of three [[protein isoform]]s of [[nicotinamide-nucleotide adenylyltransferase]] found in humans.<ref name="pmid28445802">Liquid error: wrong number of arguments (given 1, expected 2)</ref> NMNAT3 levels are highest in liver, heart, skeletal muscle, and [[erythrocyte]]s.<ref name="pmid28445802" />
NMNAT3 is localized in [[mitochondria]].<ref name="pmid29883761">Liquid error: wrong number of arguments (given 1, expected 2)</ref> [[Gene knockdown|Knockdown]] of ''NMNAT3'' [[gene expression]] in cell culture strongly reduces mitochondrial function.<ref name="pmid29883761" /> NMNAT3 is essential for maintaining [[nicotinamide adenine dinucleotide]] in red blood cells.<ref name="pmid29883761" />
As of 2017 mutations in the ''NMNAT3'' gene have not been associated with any known disease.<ref name="pmid28445802" />
==References==
[[Category:Molecular biology]]
NMNAT3 is the third of three [[protein isoform]]s of [[nicotinamide-nucleotide adenylyltransferase]] found in humans.<ref name="pmid28445802">Liquid error: wrong number of arguments (given 1, expected 2)</ref> NMNAT3 levels are highest in liver, heart, skeletal muscle, and [[erythrocyte]]s.<ref name="pmid28445802" />
NMNAT3 is localized in [[mitochondria]].<ref name="pmid29883761">Liquid error: wrong number of arguments (given 1, expected 2)</ref> [[Gene knockdown|Knockdown]] of ''NMNAT3'' [[gene expression]] in cell culture strongly reduces mitochondrial function.<ref name="pmid29883761" /> NMNAT3 is essential for maintaining [[nicotinamide adenine dinucleotide]] in red blood cells.<ref name="pmid29883761" />
As of 2017 mutations in the ''NMNAT3'' gene have not been associated with any known disease.<ref name="pmid28445802" />
==References==
[[Category:Molecular biology]]
May 28, 2020 at 04:38AM
