Wednesday, December 18, 2019

HDEL (amino acid sequence)

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HDEL (amino acid sequence)

Tinss: Added reference list


'''HDEL''' is a [[target peptide]] sequence in plants and yeasts<ref name=":22">Liquid error: wrong number of arguments (given 1, expected 2)</ref><ref>Liquid error: wrong number of arguments (given 1, expected 2)</ref><ref name=":32">Liquid error: wrong number of arguments (given 1, expected 2)</ref> located on the C-terminal end of the [[amino acid]] structure of a [[protein]]. The HDEL sequence prevents a protein from being secreted from the [[endoplasmic reticulum]] (ER) and facilitates its return if it is accidentally exported.

The similar sequence [[KDEL (amino acid sequence)|KDEL]] performs the same function in animals, while [[Plant|plants]] are known to utilize both KDEL and HDEL signaling sequences.<ref name=":3">Liquid error: wrong number of arguments (given 1, expected 2)</ref><ref name=":2">Liquid error: wrong number of arguments (given 1, expected 2)</ref>

The abbreviation HDEL is as follows.

* '''H'''—[[Histidine]]
* '''D'''—[[Aspartic acid]]
* '''E'''—[[Glutamic acid]]
* '''L'''—[[Leucine]]

Three letter code is: [[Histidine|His]]-[[Aspartic acid|Asp]]-[[Glutamic acid|Glu]]-[[Leucine|Leu]].

==References==
<references />

December 19, 2019 at 07:40AM

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